I'm a big fan of Krista Tippett's show, On Being. Week after week, year after year, she hits just the right notes in her exploration of the spiritual in a material world; her show is the perfect blend of scientific questing and spiritual questing. This week's show features physicist S. James Gates, Jr, available on audio:

He also has an essay that I highly recommend:

On the Universality of Creativity in the Liberal Arts and in the Sciences